Bunney, Tom D.: search on Z-Library

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1

Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes

Liu, Yang, Bunney, Tom D., Khosa, Sakshi, Macé, Kévin, Beckenbauer, Katharina, Askwith, Trevor, Maslen, Sarah, Stubbs, Christopher, de Oliveira, Taiana M., Sader, Kasim, Skehel, Mark, Gavin, Anne-Clau

Journal:

Year:

2020

Language:

english

File:

PDF, 2.88 MB

english, 2020

2

Signaling properties and expression in normal and tumor tissues of two phospholipase C epsilon splice variants

Sorli, Sonia Caroline, Bunney, Tom D, Sugden, Peter H, Paterson, Hugh F, Katan, Matilda

Journal:

Year:

2004

Language:

english

File:

PDF, 475 KB

english, 2004

3

14-3-3 protein regulation of proton pumps and ion channels

Tom D. Bunney, Paul W.J. van den Wijngaard, Albertus H. de Boer

Journal:

Plant Molecular Biology

Year:

2002

Language:

english

File:

PDF, 128 KB

english, 2002

4

Regulatory links between PLC enzymes and Ras superfamily GTPases: Signalling via PLCɛ

Tom D. Bunney, Rhona W. Baxendale, Matilda Katan

Journal:

Advances in Enzyme Regulation

Year:

2009

Language:

english

File:

PDF, 174 KB

english, 2009

5

Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1

Perdios, Louis, Bunney, Tom D., Warren, Sean C., Dunsby, Christopher, French, Paul M.W., Tate, Edward W., Katan, Matilda

Journal:

Advances in Biological Regulation

Year:

2015

Language:

english

File:

PDF, 6.81 MB

english, 2015

6

Association of Phosphatidylinositol 3-Kinase with Nuclear Transcription Sites in Higher Plants

Tom D. Bunney, Peter A. C. Watkins, Alison F. Beven, Peter J. Shaw, Luis E. Hernandez, George P. Lomonossoff, Mike Shanks, Jan Peart and Bjørn K. Drøbak

Journal:

Year:

2000

Language:

english

File:

PDF, 1.60 MB

english, 2000

7

Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach

Broncel, Malgorzata, Serwa, Remigiusz A., Bunney, Tom D., Katan, Matilda, Tate, Edward W.

Journal:

Molecular & Cellular Proteomics

Year:

2016

Language:

english

File:

PDF, 1.51 MB

english, 2016

8

Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System

Bunney, Tom D., Inglis, Alison J., Sanfelice, Domenico, Farrell, Brendan, Kerr, Christopher J., Thompson, Gary S., Masson, Glenn R., Thiyagarajan, Nethaji, Svergun, Dmitri I., Williams, Roger L., Bree

Journal:

Year:

2018

Language:

english

File:

PDF, 4.34 MB

english, 2018

9

The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study

Bunney, Tom D., Wan, Shunzhou, Thiyagarajan, Nethaji, Sutto, Ludovico, Williams, Sarah V., Ashford, Paul, Koss, Hans, Knowles, Margaret A., Gervasio, Francesco L., Coveney, Peter V., Katan, Matilda

Journal:

Year:

2015

Language:

english

File:

PDF, 2.14 MB

english, 2015

10

Single amino acid variation in barley 14-3-3 proteins leads to functional isoform specificity in the regulation of nitrate reductase

Mark P. Sinnige, Ilja Roobeek, Tom D. Bunney, Antonie J.W.G. Visser, Jos N.M. Mol, Albertus H. de Boer

Journal:

The Plant Journal

Year:

2005

Language:

english

File:

PDF, 1.85 MB

english, 2005

11

Phospholipase C epsilon: linking second messengers and small GTPases

Tom D. Bunney, Matilda Katan

Journal:

Trends in Cell Biology

Year:

2006

Language:

english

File:

PDF, 1.00 MB

english, 2006

12

Slow vacuolar channels from barley mesophyll cells are regulated by 14-3-3 proteins

Paul W.J. van den Wijngaard, Tom D. Bunney, Ilja Roobeek, Gerald Schönknecht, Albertus H. de Boer

Journal:

Year:

2001

Language:

english

File:

PDF, 238 KB

english, 2001

13

Phosphoinositide signalling in cancer: beyond PI3K and PTEN

Bunney, Tom D., Katan, Matilda

Journal:

Nature Reviews Cancer

Year:

2010

Language:

english

File:

PDF, 572 KB

english, 2010

14

Multiplexed FRET to Image Multiple Signaling Events in Live Cells

Grant, David M., Zhang, Wei, McGhee, Ewan J., Bunney, Tom D., Talbot, Clifford B., Kumar, Sunil, Munro, Ian, Dunsby, Christopher, Neil, Mark A.A., Katan, Matilda, French, Paul M.W.

Journal:

Biophysical Journal

Year:

2008

Language:

english

File:

PDF, 267 KB

english, 2008

15

Crystal Structure of the Human, FIC-Domain Containing Protein HYPE and Implications for Its Functions

Bunney, Tom D., Cole, Ambrose R., Broncel, Malgorzata, Esposito, Diego, Tate, Edward W., Katan, Matilda

Journal:

Year:

2014

Language:

english

File:

PDF, 3.32 MB

english, 2014

16

Dynamic Allostery in PLCγ1 and Its Modulation by a Cancer Mutation Revealed by MD Simulation and NMR

Koss, Hans, Bunney, Tom D., Esposito, Diego, Martins, Marta, Katan, Matilda, Driscoll, Paul C.

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 3.33 MB

english, 2018

17

Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET

Perdios, Louis, Lowe, Alan R., Saladino, Giorgio, Bunney, Tom D., Thiyagarajan, Nethaji, Alexandrov, Yuriy, Dunsby, Christopher, French, Paul M. W., Chin, Jason W., Gervasio, Francesco Luigi, Tate, Ed

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.12 MB

english, 2017

18

High speed unsupervised fluorescence lifetime imaging confocal multiwell plate reader for high content analysis

Clifford B. Talbot, James McGinty, David M. Grant, Ewan J. McGhee, Dylan M. Owen, Wei Zhang, Tom D. Bunney, Ian Munro, Beverly Isherwood, Rob Eagle, Andre Hargreaves, Chris Dunsby, Mark A. A. Neil, Pa

Journal:

Journal of Biophotonics

Year:

2008

Language:

english

File:

PDF, 1.29 MB

english, 2008

19

ATP-dependent regulation of nuclear Ca2+ levels in plant cells

Tom D. Bunney, Peter J. Shaw, Peter A.C. Watkins, J.Philip Taylor, Alison F. Beven, Brian Wells, Grant M. Calder, Bjørn K. Drøbak

Journal:

Year:

2000

Language:

english

File:

PDF, 293 KB

english, 2000

20

Cold Urticaria, Immunodeficiency, and Autoimmunity Related to PLCG2 Deletions

Ombrello, Michael J., Remmers, Elaine F., Sun, Guangping, Freeman, Alexandra F., Datta, Shrimati, Torabi-Parizi, Parizad, Subramanian, Naeha, Bunney, Tom D., Baxendale, Rhona W., Martins, Marta S., Ro

Journal:

Boston Medical and Surgical Journal

Year:

2012

Language:

english

File:

PDF, 907 KB

english, 2012

21

NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 3 in apo state and in complex with inhibitor PD173074

Sanfelice, Domenico, Koss, Hans, Bunney, Tom D., Thompson, Gary S., Farrell, Brendan, Katan, Matilda, Breeze, Alexander L.

Journal:

Biomolecular NMR Assignments

Year:

2018

Language:

english

File:

PDF, 1.91 MB

english, 2018

22

14-3-3 adaptor proteins are intermediates in ABA signal transduction during barley seed germination

Peter J. Schoonheim, Mark P. Sinnige, Jose A. Casaretto, Helena Veiga, Tom D. Bunney, Ralph S. Quatrano, Albertus H. de Boer

Journal:

The Plant Journal

Year:

2007

Language:

english

File:

PDF, 814 KB

english, 2007

23

Autoimmunity and Inflammation Due to a Gain-of-Function Mutation in Phospholipase Cγ2 that Specifically Increases External Ca2+ Entry

Philipp Yu, Rainer Constien, Neil Dear, Matilda Katan, Petra Hanke, Tom D. Bunney, Sandra Kunder, Leticia Quintanilla-Martinez, Ulrike Huffstadt, Andreas Schröder, Neil P. Jones, Thomas Peters, Helmut

Journal:

Year:

2005

Language:

english

File:

PDF, 800 KB

english, 2005

24

Targeting the Src Pathway Enhances the Efficacy of Selective FGFR Inhibitors in Urothelial Cancers with FGFR3 Alterations

Lima, Nadia Carvalho, Atkinson, Eliza, Bunney, Tom D., Katan, Matilda, Huang, Paul H.

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 2.96 MB

2020

25

RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity

Frankel, Paul, Aronheim, Ami, Kavanagh, Emma, Balda, Maria S, Matter, Karl, Bunney, Tom D, Marshall, Christopher J

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 361 KB

english, 2004

26

Structural Insights into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2

Tom D. Bunney, Olaniyi Opaleye, S. Mark Roe, Petra Vatter, Rhona W. Baxendale, Claudia Walliser, Katy L. Everett, Michelle B. Josephs, Carolin Christow, Fernando Rodrigues-Lima, Peter Gierschik, Laure

Journal:

Year:

2009

Language:

english

File:

PDF, 1.36 MB

english, 2009

27

Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use

Patani, Harshnira, Bunney, Tom D., Thiyagarajan, Nethaji, Norman, Richard A., Ogg, Derek, Breed, Jason, Ashford, Paul, Potterton, Andrew, Edwards, Mina, Williams, Sarah V., Thomson, Gary S., Pang, Cam

Journal:

Year:

2016

Language:

english

File:

PDF, 5.88 MB

english, 2016

28

A Hypermorphic Missense Mutation in PLCG2, Encoding Phospholipase Cγ2, Causes a Dominantly Inherited Autoinflammatory Disease with Immunodeficiency

Qing Zhou, Geun-Shik Lee, Jillian Brady, Shrimati Datta, Matilda Katan, Afzal Sheikh, Marta S. Martins, Tom D. Bunney, Brian H. Santich, Susan Moir, Douglas B. Kuhns, Debra A. Long Priel, Amanda Ombre

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

29

Dysfunction of phospholipase Cγ in immune disorders and cancer

Koss, Hans, Bunney, Tom D., Behjati, Sam, Katan, Matilda

Journal:

Trends in Biochemical Sciences

Year:

2014

Language:

english

File:

PDF, 891 KB

english, 2014

30

PLC regulation: emerging pictures for molecular mechanisms

Tom D. Bunney, Matilda Katan

Journal:

Trends in Biochemical Sciences

Year:

2011

Language:

english

File:

PDF, 558 KB

english, 2011

31

Nuclear Ca 2+ -fluxes and phosphoinositides in plants

BUNNEY, TOM D., CALDER, GRANT M., SHAW, PETER J., DRØBAK, BJØRN K.

Journal:

Biochemical Society Transactions

Year:

1995

Language:

english

File:

PDF, 203 KB

english, 1995

32

Projected sea level rise and changes in extreme storm surge and wave events during the 21st century in the region of Singapore

Cannaby, Heather, Palmer, Matthew D., Howard, Tom, Bricheno, Lucy, Calvert, Daley, Krijnen, Justin, Wood, Richard, Tinker, Jonathan, Bunney, Chris, Harle, James, Saulter, Andrew, O&amp, apos, Neill, Cla

Journal:

Year:

2016

Language:

english

File:

PDF, 2.19 MB

english, 2016

33

Severe Autoinflammatory Manifestations and Antibody Deficiency Due to Novel Hypermorphic PLCG2 Mutations

MartÃn-Nalda, Andrea, Fortuny, Claudia, Rey, Lourdes, Bunney, Tom D., Alsina, Laia, Esteve-SolÃ©, Ana, Bull, Daniel, Anton, Maria Carmen, BasagaÃ±a, MarÃa, Casals, Ferran, DeyÃ¡, Angela, GarcÃa-Pra

Journal:

Journal of Clinical Immunology

Year:

2020

File:

PDF, 1.90 MB

2020

34

Structural and Mechanistic Insights into Ras Association Domains of Phospholipase C Epsilon

Tom D. Bunney, Richard Harris, Natalia Lamuño Gandarillas, Michelle B. Josephs, S. Mark Roe, S. Caroline Sorli, Hugh F. Paterson, Fernando Rodrigues-Lima, Diego Esposito, Chris P. Ponting, Peter Giers

Journal:

Year:

2006

Language:

english

File:

PDF, 997 KB

english, 2006

35

Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation

Tom D. Bunney, Diego Esposito, Corine Mas-Droux, Ekatarina Lamber, Rhona W. Baxendale, Marta Martins, Ambrose Cole, Dmitri Svergun, Paul C. Driscoll, Matilda Katan

Journal:

Year:

2012

Language:

english

File:

PDF, 4.30 MB

english, 2012

36

Backbone1H,13C, and15N Resonance Assignments for the two 13

Richard Harris, Tom D. Bunney, Matilda Katan, Paul C. Driscoll

Journal:

Journal of Biomolecular NMR

Year:

2005

Language:

english

File:

PDF, 166 KB

english, 2005

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